Put the two of them (10 and 36) side by side and you'll see a significant size difference. There's also a substantial weight difference, with the 10 weighing at least 1/3 more than the 36. The 10 is powered by a leaf spring, the 36, by a coil spring. Generally, you'll find that the trigger on the 10 is considerably lighter than that of the 36.
Others have mentioned that the 36 is a five-shot revolver whereas the 10 is a six shooter. Another significant difference between the two guns is the sights. I find that it is much harder to visualize the tiny ramp front sight on the 36 than the considerably bigger and thicker front sight on the 10.
I would rate the 10 (or its stainless brother, the 64) as a superior gun for range work and, perhaps, for general carry. My primary defensive weapon is a 64 snub. For me, the greater weight and bulk of the gun are more than compensated for by its better trigger, its greater capacity, and its much better sights.
On the other hand, a 36 is more easily concealed than is the 10. One can carry a 36 in his pocket or her purse without difficulty. IMO, the 36's ease of concealment is its greatest asset.
That said, both are super guns.