It all boils down to what your looking to do with it. Both are excelent hunting revolvers, but each one has it's own pro's and con's. IMO, the .460 is a more versitile handgun, being able to fire .45LC, .454C, and the .460MAG. Almost every sporting store, including Dick's and Wal-Mart will have .45LC, so finding ammo will be alot easier. Finding ammo for the 500MAG will be a bit tougher and more expensive, but the power behind that slug is second to none. Reloading is generally a must if you plan on shooting either gun frequently, but spend the time to ask around and look for threads on this forum comparing the two weapons. Each revolver and caliber provides it's own special purpose and use, but as I stated above, it all depends on what you want to do with it. Hope this was helpful!