I use 2400 for my full house magnums, .357 and .44, andi use it a lot in the old "Skeeter Skelton 158 LSWC .357 in a .38 case, crimped on the top lube groove" load. My revolvers love it. I use Unique for .45 acp, .38 Special, 9mm, .40 S&W, 45 Colt, .44 Special. And I use Unique for mid level...