Thanks everyone for the responses. I am now on the fence with ever shooting it. I went through some of his things yesterday, and I was able to find a box of "Fifty(50): Herter's Select Grade .38 Special, 158 grain FMJ, Brass Case. (made by Sellier & Bellot)", along with a note that read "never fired".
I can see why you all think it would be a good idea to preserve it, but I don't think I'd enjoy having it sit in a safe. On the other hand, learning to shoot his gun would bring back some good memories and make me feel closer to him. I'm not much of a collector, and personally might get more personal value out of shooting it. I am still undecided so we will see. The receipt, box, manual, and cleaning kit were all with it, and were very cool to read through. If anyone is interested I can post some more pictures.