Many years ago, before he got out of Dodge and moved to VT, I was at Karl Sokol's shop,
Chestnut Mountain Sports, back when it was in Sunderland, MA. He had a 5" S&W 625 .45acp that looked just a little better than the 29 pictured in this thread. The cylinder looked the same, but the topstrap was still attached to the gun, but had a large bulge in it now. The owner was a pin shooter using a light charge of a fast burning powder. I don't remember what powder it was though. It was assumed that the shooter double charged the case.
When I started reloading, it was on an RCBS Rockchucker. Check the powder levels, and you'll be fine. Then, my father "upgraded" to a Lee progressive. Their powder measures suck. More squib loads than you would imagine.
Then, we got a Dillon SDB. Their powder measures hold a charge extremely accurately, and the SDB auto indexes, so you don't have to worry about an overcharge, either. I still use a bright desk light shining into the case and visually verify the level of the powder as I seat the bullet at station #3 though. Only out of habit, since I've never once, in the past 22 years of using that same press, two factory rebuilds and hundreds of thousands of rounds, caught an abnormal powder charge from it.