I have a few rifle/pistol combos, most I try to settle on the same load for both, but in the case of .45 Colt or .32-20 I have a 'hotter' load for the rifle, as mentioned this can lead to serious consequences if mixed up.
While the suggestion for labelling the box is good, and needs to be done, what I do for the higher pressure rounds is to take a big fat Sharpie or some other permant marker in Red ink and run it over the base and primer of each higher pressure cartridge, just put them in an ammo box insert and run it over the bases.
This will immediatly show up when chambering either rifle or revolver/pistol load.
The scenario of having two boxes of ammo on the bench at once, one higher pressure and one safe for the revolvers and having the individual rounds getting mixed up is too real. With the red bases it is an immediate 'Flag' so to speak to catch the eye.
The Sharpie ink wont affect the primer and after tumbling comes off. Usually tho' it is best to keep the higher pressure cases seperate from the low as case streching will shorten the life of the case.
Hope this helps.
RD