Nice find! Rimfire ammunition was quite common until about WW2, but very little has been produced since that time. The variety is great, in calibers from .22 (dozens of different versions), .25, .32, .38, .44 and probably others. Many of the boxes contained specifics of which firearms for which the cartridges were suitable, usually listing makes, models, and pistol or rifle types. Some were offered in "short" and "long" versions.
There were .32 rimfire revolvers offered by a dozen or more different makers, and a number of rifles also. S&W, Iver Johnson, H&R, Colt, and many less well known brands. Some used a version of a standardized cartridge, but many used only the manufacturer's proprietary cartridge designs. Millions of rimfire guns from 1860s through 1920s or so remained in use for many, many years.
The lack of specific instructions on the CIL-Canuck box shown indicate to me that this example is a standardized (or generic) type, probably suitable for many of the early guns. At this point in time I think this find is far more interesting and valuable to collectors than for any actual shooting purposes.
Last rimfire ammunition I saw offered on a retail basis was some imported and sold by Navy Arms company, and that was probably 40 years ago.