I haven't own a 45 ACP with a Ti cylinder. But, since 45 ACP isn't a magnum cartridge that uses magnum powders like H-110, or Winchester 296, you won't have to worry about cylinder erosion.I'm seriously eyeballing a 325 PD in an LGS and just wondering how well they hold up vs steel.
Never owned a scandium or Ti gun. I understand they must be cleaned carefully.