Thanks for all the suggestions!!!
When the chambers are clean, everything except Aguila seats easily- Aguila needs a good push. After 60 or 70 rounds I have to give everything a good push to seat it, I do check that.
I cleaned the firing pin hole by spraying in Breakfree while moving the pin back and forth, did that from both ends, then blew it out with compressed air.
Fired 30 rounds of CCI SV, 3 failures to fire. Each time I then rotated the cartridge 180 degrees, they fired the second time. the indent from when they fire is deeper than the indent from when they don't.
I then pulled the mainspring, the only washer I had that would fit was unfortunately nylon, so it might have inconsistent seating or compression. It's 0.03" thick. The spring did not look like it had been trimmed, both ends had the last coil pressed against the previous coil the way they come from the factory.
Then fired 20 rounds of CCI SV, 1 failure to fire. Then 8 rounds of Fiocchi standard velocity and 50 rounds of mixed higher velocity- Blazer and Aguila Super Extra. One failure with an Agulia (and it is possible it didn't seat all the way), other than that everything was good.
Next step, I'll order a replacement spring. I see Numrich has some that they say are new factory original. I'll also give it more deep cleaning.
Mainspring, New Factory Original J FRAME REVOLVERS SMITH & WESSON
One thing not mentioned yet is tight chambers. If there is any resistance to seating the bullet, and it is not fully seated the first blow to the cartridge may just push it deeper to seating and not set it off. Try loading by pushing hard to fully seat all rounds, see if that does anything to help. If so, reaming the chambers with a finishing reamer can help this problem.