That particular number would probably only be of significance to what I would imagine to be a small handful of collectors who look for things like that. How significant would depend on how badly that collector wanted it. If he had a large collection of different models, each with a serial number which matched the caliber, maybe a lot. Just that one example, maybe a little, but I wouldn’t think a whole lot.
Now the first gun in a production run, HTR0001 for example, would be much more likely to bring a premium, especially in highly desirable models. Just MHO, but I’ve been a serious collector for quite a while.