I'm speaking in very general terms as there are exceptions, but with handgun bullets, cast flat base versus bevel base accuracy is hard to predict. If bullet fit, alloy, pressure, etc. is right, there should be very little, if any, difference in accuracy between the two designs.
Someone else here may remember more about this than I, but there was mention of the flat vs. bevel topic, I think, in the NRAs book CAST BULLETS, primarily a compilation of cast bullet articles and experiments by AMERICAN RIFLEMAN technical staff member Col. E.H. Harrison. That was when AR had a technical staff and published technical gun and handloading articles. Articles and information are mostly from the '60s, but the material remains useful today. I think Harrison found the H&G #50 flat base wadcutter was slightly less accurate than the #50 bevel base version. Again, I'm not positive on this; been a long time since I read it.
Completely different story with boattail rifle bullets. I'm not sure they can really be compared with bevel base cast handgun bullets. Usually, a flat base rifle bullet is at least slightly more accurate than a boattail counterpart. When working up a handload and I have a choice, I'll go with the flat base design first as it will probably shoot better.
If one chooses a boattail design these days, however, it will likely still shoot very well. With the current long range fad, boattail bullet designs are far more popular. While they have a higher ballistic coefficient than a flat base design, this only becomes an advantage when ranges exceed 300-400 yards and beyond. At shorter distances, flat base designs will often shoot more accurately. With today's superior bullets and very accurate rifles, the differences may be very small.