Pace,
I do not a before and after comparison with my 625 PC which is factory chamfered, but I really like it.
I have shot a lot of other revolvers over the years with speed loaders, and my 625 is much easier to charge with 45 AR than past revolvers without the modification. My 625 with moon clips is very fast. I cannot do a side by side to say "x" amount faster, but I do think they help.
But, a lot of gain can be related to the type and shape of your bullet. Also by how rigidly your moon clips hold your rounds. My TK clips do a good job at holding my rounds. Pretty much any bullet shape is a quick fit. With the polymer clips, even fmj's take a touch of jiggling. SWC's with the polymer clips are much slower. The chamfering probably helps with these, but the combination is not one in which I try and go fast.
I would also note that your 610 is a great 10mm gun as compared to a semi-auto in that you have full case support. I do not have one to see how much the lower web of the case (overhang) might be impacted by chamfering, but it is something for which I might want to do a bit of research, beyond just the speed of chambering. And it is something for which doing yourself might require a good bit of care.
Craig