Yes. Quoting myself, "...very slight changes in components can make a huge difference in pressure."
Touchy? Okay, but I have not noticed that in any of the loads I have used this powder in. In fact, that is why I use it for the loads I do. It seems to be kind of forgiving at the upper end of things. Not that you cannot get flattened primers or sticky extraction with it, I just never have and like Dragon, I have loaded some mighty stiff 44Mag loads for a carbine.
Since firearms are individuals, maybe yours react as your post states, mine don't seem to.
Caution to another loader is a good thing, just with H110/W296, I like the fact that a maximum load comes right to the base of the bullet and at that point, gives consistent performance. Touchy to me is when you go from "4.2gr" of a powder to "4.3gr" of the same powder with the same components and you get vastly different results. Flattened primers, sticky extraction, wide swings on the chronograph and the like. W296/H110 does not do that. If you are using "21.5gr" and everything is okay, and go to "21.6gr" things are going to be a bit different but not drastically. Now, going to "23.5gr", if you can get it in the case, is going to give you vastly different results, but that would be expected by most folks and not considered "touchy".
It is kind of like describing "sticky extraction". One person thinks it is when you have to use a lot of thumb pressure on the ejector rod, another believes that it is only when you have to drive them out with the edge of the table or a mallet.
Touchy and W296/H110 are not two words that I use to in the same sentence ever.
FWIW