I shoot my 625's for enjoyment with target loads (4.0 grs of Bullseye with a 200 gr SWC or equivalent).
However, in preparing myself for my traditional deer hunting (I did this routinely for several years) I would shoot about 2500 full loads of .44 magnum in my two hunting revolvers (8 3/8" S&W Model 29 and 7.5" Ruger Red Hawk). Both of these have scopes mounted so the extra weight does reduce felt recoil a good bit. Further, I would shoot the .44 magnum with full loads during the year on steel up to a hundred yards from various field positions just to maintain my skill level.
I was reading J.D. Jones' shooting magazine at the time, and became intrigued with the possibilities of heavier loads in the TC Contender platform. I bought several TC barrels evenually, and found the load that exceeded my recoil tolerance. It was the .444 Marlin in a 10" barrel TC Contender. THAT was too much. It had iron sights (no scope weight to reduce felt recoil) and each time I fired it, it would twist from my left (support hand) and bend my right wrist to the point that I realized if I continued, it would physically injure me. I sold the Marlin barrel.
Then I bought a J.D. Jones custom barrel for the TC chambered for the .375 JDJones. Now, this cartridge has the same recoil as the .444 Marlin. It is built on the same case and drives a 270 gr .375 bullet at up to 2000 fps. However, this barrel had JD's porting, and it had JD's super strong scope mount. I mounted a 2X Leupold on this scope and started shooting it. I learned that if I would limit each string to five shots, I could get five surprise breaks (shooting standing two handed). The muzzle brake prevented ANY muzzle rise (but did little for the "come back"). Eventually, I came to shoot the best target I have ever shot with the heavy recoiling pistol. Shooting five shots, then going to another target and shooting my 16-4 S&W with .32 target loads, then shooting the second five shots with the .375, I shot a 100x100, 10"X" possible at 25 yards (on the timed fire target). Now, that was a pretty target. I have not done it since but I CAN shoot that handgun quite well AS LONG AS I LIMIT MYSELF TO FIVE SHOTS IN A STRING).
So, I was armed quite well for hunting. The only problem is that I did all of my deer hunting in Ohio and that handgun is not legal here. So, I never shot anything live with it.
I DID establish my limits however, and from an academic stand point, it was interesting and instructive.
Now, I think I'll go out to the range and ENJOY myself with my 625's and target loads...
Dale53