Of course, home defense means any number of things. In the average, residential subdivision, taking a 300 yard "self defense shot" with a "battle rifle" is gonna be dern tricky to explain to the DA unless and until civilization collapses.
Now, if someone just wants a rifle, I don't care, I like rifles, and have quite a few myself.
Now, if you are Iggy's next door neighbor, as it is, and his house if a 45 minute hard drive from yours, then the need for a LONG range SD rifle seem to be more likely, certainly if you are in bear country as well (sorry, i just had to throw that in there)
Now, if you just want a rifle, then get all the rifles you want. However, for defending hearth and home against any reasonable threat as long as the courthouse is still functioning, and if you live anywhere near "town", then I suggest as others do a good lever gun, or a basic AR package. However, virtually any shoulder fired weapon can and has been used for home defense, so you should get the rifle YOU like, and you can use it for any number of purposes....including self defense