I know nothing of the specific loading. I can see its outrageously expensive, more so that most centerfire range ammo.
I'm also distrustful of the data sheet that uses the 380 as a comparison, and shows its not even that good. The 380 has always been a suspect round for self defense. Its like buying a new car and saying "its almost as good as a used Yugo."
All that said, I do have a 351 and I like it. Shooting the 22 mag isn't a cheap thing to do, but necessary to prove your handguns reliability. My son even stopped over the other day to borrow my gun. He was taking his wife and another couple to the range to show them different guns. Guess which they all liked the best!
He even used it for his range portion of the CCW license requirement here.
I had maybe 7 or 8 boxes of ammo for it last year. Then our gun show partner was selling her stock off. She'd been lugging it around from show to show, trying to get the $7 sticker price back out of it. At about the 3rd or 4th show, I told her I'd give her $5 a box at closing time. She had the advantage of trying to sell it all weekend, but a floor if she wanted so she wouldn't have to take it back home. She thought about it for a few minutes, then slid it across the table to me. The point being its a very expensive round to be messing with. Buying "self defense" versions more than doubles the price.
We have an advantage with revolvers. At least it doesn't jam. But be very wary of your firing pin weight. If you modify your hammer spring (think Wolfe kits), it very possibly will become unreliable. Trust me, I did it and had to change it back.
