No, but improper disassembly and reassembly, especially with ill fitting acrewdrivers and poor attention to details such as spring alignment,etc, along with dragging the cleaning rod on the muzzle and a host of other things that negatively impact the overall well being of the gun can bring about "ruination" to your gun. A wipe down or even a pass or two of a patch through the bore isn't going to hurt anything, but guys who feel the need to detail strip their gun after each outing are, IMHO at least, doing more harm than good. As a parts vendor friend of mine once observed, "It's guys like you that keep guys like me in business!"
Froggie