It's especially fun when the starting load in one manual is beyond max in another!
I understand the "different conditions" disclaimer, but come on. We are long past the point in instrumentation where there should be that much variability.
As others have said: Pick something in the middle of the range, load, enjoy.
Different bullets can have distinctly different pressure profiles. Something I learned first hand using Speer's data for a 140 grain bullet with a 140 grain Hornady XTP in 357 Magnum. A load that was well below Speer's maximum caused sticky extraction with the Hornady bullet. Turned out that "moderate" load was 0.2 grains over Hornady's maximum with the powder I was using.
It's why that old rule about "Start Low and Work up" came about. Something that I've always payed attention to but in my case I was "working up" with only 5 rounds at each charge level. As I learned 5 rounds isn't enough to get an accurate picture and I now do my testing with at least 20 rounds.
Like others have mentioned the best accuracy usually occurs at charge levels somewhere between the mid range and maximum charge for a specific bullet. However, there are problems with applying that rule universally without any due dilligence.
First, you need to be working with data for your specific bullet and powder. So, if you don't have an exact match the safest approach is the conservative one.
Second, barrels can have unique pressure curves and you won't know if your barrel is "tight or loose" until you have some experience loading for your barrel. Thus, starting low and working up is still the best approach.
Third, as I have recently discovered with CFE223 some powders don't operate well or cleanly at low or moderate charge levels. Probably due to being somewhat pressure sensitive for complete ignition. As I recently found out after scoring an 8 lbs. keg of CFE I've been working up loads and the first two session left the bolt carrier group looking like a diesel locomotive had been exhausting into it for a few years. Yesterday I tested loads with two different bullets loaded just 4/10ths below the maximum recommended charge. After 20 rounds with each bullet the bolt carrier was much easier to clean and in both cases the produced accuracy was distinctly improved.
BTW, that Copper Fouling Eliminator aspect actually seems to be more than just Hype, because my barrel is now completely free of
ANY trace of copper fouling. I can also report that CFE223 meters about as well as H110, which means it's one of the finest metering powders on the planet. Just wish I didn't have to push it as hard as it seems to require. Because barrels do last longer if you shoot at somewhat moderate velocities.