At one point in the early 1980's, a buddy and I owned half each of a Ransom Rest and a good chronograph. We set out to find the best gun and ammo combination we could, from primarily an accuracy perspective. We shot the bolted-down revolvers at both 25 and 50 yards.
For ammo, we bought 148 grain hollow base wadcutter ammo from W-W, R-P and Federal and also assembled handloads using Speer, Hornaday and Remington-Peters swaged lead bullets of the same weight and design, only loaded by ourselves.
We also handloaded some 158 grain round nose and lead semiwadcutters into both Special and Magnum cases, and then as long as we were there, loaded some wadcutter bullets into Magnum cases with enough of the same powder to equal the velocities between the bigger and smaller case.
I decided to try some full power jacketed bullet ammo and handloads, too. I had several boxes of Federal 125 grain Magnums and Winchester 145 grain Silvertips. I handloaded some Sierra 158 grain jacketed soft points into both Special and Magnum cases using powder charges that duplicated the ammo factories' products.
For guns, we had 2 K frame revolvers, a Model 10 and a Model 15, that had been converted into PPC guns, with very heavy barrels and top ribs with multi-position, quick-adjust front sights. We had a couple pair of 6" Model 66's, a 6" Model 19, 2 6" M-14's, a 6 inch Ruger Security-Six, a 6 inch Highway Patrolman and 8 or more Model 27's, one a Registered Magnum, with barrels running from 5 inchs through 6 and 6-1/2 inches, one 7-1/2 incher (the Registered Mag) and 2 8-3/8 inchers. My partner had his Colt Python (6) and a Trooper (also a 6 inch).
Several of the guns were near twins. We expected to find some clear-cut trend, perhaps on make or model or even frame size to lead the accuracy testing, but we didn't.
Just about every gun bolted in and shot was top performer with one cartridge loading, or very very close to the top. No frame size dominated. No barrel length dominated.
The smallest 6 shot group was fired my my old 7-1/2 inch Registered Magnum with the handloaded Sierra 158 gr.jsp, very closely followed by the Winchester 145 gr. Silvertip
The absolutely smallest 5 shot group was fired by my 2 inch blued Cheifs Special shooting my cast 158 gr SWC or my Sierra 158 gr. JSP.
If I had to pick a single cartridge that shot the best in most of the guns, it was Federal's 125 gr jhp factory load fired from the Magnums. All of them, S&W K, L and N guns, the single Ruger and both Colts shot this very nicely.
The best wadcutter load was the factory Remington-Peters stuff, beating out the W-W and our Speer bullet handloads by an average of under 1/2 inch for 6 shots at 25 yards Oddly, the Ruger, the Colt Trooper and one 6-1/2 inch Model 27 routinely shot them into 3-4 inch groups, double the size of the better groups from other guns.
We repeated the test a month later with just .357 Mag revolvers and just Magnum ammo. We added 2-1/2 and 4 inch guns, a 7-1/2 inch Blackhawk and a 10 inch T/C Contender, mostly concerned with barrel length's affect on velocity. That is a whole nother story.
We concluded that it was impossible to predict which revolver was going to be consistently the most accurate. Couldn't do it by manufacturer, frame size or barrel length when bolted into the mechanical rest. They all had moments of excitement.
None of them were absolute dogs, though,
I wish that we would have had more L framers to shoot but they were new then and scarce.
Overall, the most generally accurate .357's (meaning they shot several loads very well) were all N frame S&W's with the exception of a 4 inch Model 19. I expected the Python to do better but it had had the original barrel broken and replaced and I believe the original barrel would have done better, from the little shooting I did before the Python's forcing cone let go.
In answer, I don't think you can predict which gun will shoot the most accurate for you. Find one that you can install grips that fit your hand and that has sights your eyes like. Spend some time leaning the trigger pull properties. Try several varieties of good ammo.
Off-hand, I would have chosen a Model 27 or 686 from the group we tested.
So you go buy the one you "take a shine to" that fits your hands and you will find that it will take tons of practice and possibly some professional training before you make that gun shoot up to it's full potential.