Which big bore to get?
I've shot & loaded for both the 460 & the 500. Without a question they're a HOOT to SHOOT!! Crazy power & a wide range of bullets available. Recoil is surprisingly managable with comp'd guns. Bullets for the 460 (.452") are far more common on the shelf than the 500 around here. Unless I'm missing something though, reduced load info is far & few between on either, in any variety, from powder/bullet manufacturers. I'm sorry, I like a variety of power levels in all my magnums. (I don't drive my muscle car with the gas floored all the time, though it'd be interesting, for a while.

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(I'm going to assume you'll reload as I can't see how anyone without deep pockets could justify buying & shooting one of these otherwise.)
If I had to have only one (thankfully not) I like the 454 Casull. It can't quit match the 460 for max power, but not by much. Grain for grain, powder wise, it's more efficient than the 460. The 460 needs 8-10grs. (reference Hornady #8) more powder just to reach the same velocity with the same bullet/powder combo. Of course, all the same 460 bullets are available for the 454C too. The cases are cheaper (1/2 price). When shooting 45 Colt in the 454C, vs the 460, there's less of a jump from the case mouth to the throat (~.100" vs ~.500") which helps especially with lead bullets.
The 454C's minuses, IMO, are it's small rifle primers, some what restricted cylinder lengths, & the (biggie) fact that S&W doesn't make a gun dedicated solely to it.
But if you just want the biggest & baddest, go with the 500! Just try it before you buy it!
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