Well we can't carry here yet (although it just passed the state senate, woohoo!) I plan on carrying the 4003 safety off, in fact one of these days I am going to send it to S&W to have it converted to decock only
When you think of it, how is a loaded (one in the chamber) 3rd gen pistol carried decocked and "off safe" any different than carrying a loaded DA revolver, as far as being any more or less unsafe?
I keep my 4506-1 decocked and off safe and treat it like any other loaded handgun at home or a field.
We left-handers have a history of dying younger than our right-handed counterparts due to the lack of ergonomically correct tools. (It's true, look it up!).
Smith and Wesson was thoughtful enough to provide a safety lever I can actually use as it was intended so by God I am going to use it!