I reported on my Ransom testing of 4" model 66 back in July. I was able to show that I can put 10 shots in < 2" at 50 yd with my 66.....and that's with just one bullet and 3 different powders ... imagine all the possible combinations of a dozen bullets and 20 powders that I might try.
There is definitely a learning curve and I suggest one read all they can on the subject before using it the first time. There are principles involved that, if not understood, will lead to frustration and false conclusions.
For instance, the over arching concept is "returning to battery." Understand what that means.
Understand you may fire as many as 30-40 rounds in preparation for shooting the first group with a different gun.
ALL groups should be round ... it's a law of the shooting universe. That's why 10+ shot groups are preferred....to give that random, round group shape enough opportunity to develop. Understand what vertical and horizontal stringing is telling you ... then fix it.
There is no aiming point or "bullseye" necessary other than to get the group "on paper." You are shooting for precision, not accuracy ... understand the difference. There is no point in checking the sights after every shot. If you've properly anchored the rest and used good technique in fire control and re-setting, the sights will be pointing at exactly the same spot. If not, you have a major foul-up and it will be obvious on paper; you won't have to check the sights to know it.
If you're testing a 1911, research a "Marvel cut." Understand what it is and how it relates to the fact the first shot from a 1911, or any shot "hand fed" should not be included in the group. If you plan to shoot more than the number of rounds a magazine holds ( such as 10-shot groups with 8 round mags) learn to shoot a partial mag, drop it, and insert a new loaded magazine while the chamber is closed on a live round.
To begin, insert a loaded mag, hand chamber a round and shoot 1 or 2. Check to see if they are located on paper about where you want. If possible, DO NOT, move the gun/rest to re-aim, but rather put up a fresh piece of paper centered over the group and proceed to shoot for group. See for yourself that the first, hand-fed round, would usually (but not always) constitute a flier.
If you're a handloader who ENJOYS load testing, you'll have fun. If you're not much into testing/experimenting, but just looking for "the answer", you'd be better off paying someone to test your ammo.
If you don't already use a chronograph regularly, Id suggest you're nowhere near nerdy enough to invest in a Ransom Rest.
Ransom testing a Model 66