No really big issues; I have two of them and enjoy both. Most have cylinder throats that measure at least .453" and up. Some I've heard even have had .456" throats.
So, if you reload, you just get the .454" dia. bullets and go with it. They still shoot very nicely even with the large throats.
I've heard the Model 625 has .452" throats, but someone else will need to verify.