When I carried a S&W Model 25-2 4" .45acp I discovered that a HKS Double speedloader pouch would accept four full moon clips (first clip bullet down and second clip bullet up). I also carried a 12 round cartridge slide with 12 .45AR cartridges. I was a lot younger (a lot younger) and the weight was not a problem. In that era I liked W-W Silver Tips. (for werewolves and possible jealous husbands/boyfriends).
I did the same when I carried a M625. I didn't carry any other rounds.
Back in 1976, I carried a S&W 1917 loaded with .45 ACP rounds in half moon clips, with .45 Auto Rim cartridges in drop boxes.