What animals are predators to the skunk?
Believe it or not, cougars will take one occasionally.
We had an over-population of skunks, raccoons, and foxes at our last place. All three were heck on chickens, ducks, and geese around the barnyard.
I trapped them with a live trap. Could dispatch the foxes and raccoons just by walking up to the trap and using a .22. With skunks, however, I stood 25 yards away and shot for the head. Used my Ruger M7722 with a 1.75 x 4 power scope shooting CCI mini-mag hollow points. Ninety-five percent of the time is was a one-shot kill, but they
always released. Sometimes almost immediately, other times within five or ten minutes or so. Yep, the minute those ol' sphincter muscles relaxed...PHEW!
I'd always have a hole dug before I shot the skunks. That way, I could shot them and dump 'em in the hole before things got too bad. Usually, the smell could be minimized by throwing a couple of shovels full of dirt over the area where the trap sat and where the skunk released. Even with that, however, it was pretty evident to all within the vicinity that we'd had skunk problems.
Skunks are infamous for being carriers of rabies. We would occasionally see them in the daytime, walking around in a stupor. Sure sign that they were sick.
Looking back on it, I've probably shot enough skunks in my lifetime to make Ms. Judy a fur coat with matching handbag and set of slippers.