Sure you can use it, and I suspect it will work fine. You won’t have setback problems in a revolver. You’ll have bullet-pull problems. Unless you are using a lightweight revolver, I doubt that will be a factor. Keeping your brass trimmed to the proper, uniform length is essential to getting good crimps. I believe that’s the case no matter what tool you use, whether roll, taper, or factory-crimp die type. If you’re gun is a 340PD, or something similar, you might be heading for a little experimenting.