SIG P-220 will be along soon, I guess. But he's carried his as a FBI special agent for about 30 years and is delighted with it. The Bureau is mostly Glockland these days, but his gun is grandfathered-in.
My son and his wife have several SIG's and really like them. That says a bunch, as he is especially a Colt Govt. Model .45 and Browning HP fan.
Both the Euro and American P-220's fit my hand VERY well, about as well as any pistol ever has. I think I slightly prefer the American grip frame. The rounded hammer will not jam you in the ribs like the older pointed one might, given appendix carry in an inside the waistband holster.
I prefer the older, basic gun. I hate those big duck - tailed tangs on any guns, inc. 1911's.
There were slide rusting issues with some SIG's. Others here know more about that than I do. Doesn't apply to stainless slides, though.
I'd stay with the 4.4 inch barrel. The .45 needs barrel length to do its best, and you're already at less than the original 5" length of a 1911.
If the high bore axis doesn't bother you and the slide doesn't rust, you should be very happy with the P-220. And if the slide rides higher than on some guns, you are less likely to get the recoiling slide trapped in the cuff of your parka, as a Browning 9mm once did to me. I went back to revolvers for cold weather carry. Thank God, that didn't happen in a fight; it was on the range. Took awhile to get the slide/tang loose and I had to remove the parka.