Cylinders and timing
The above posts also reflect my experience. I served as a police armorer for three decades, and during the first half of that career worked on revolvers. Having been through the Smith revolver school and having repaired and maintained hundreds of Smith revolvers, I can tell you that virtually any part inside a Smith revolver that has anything to do with the rotation and lock up of the cylinder requires a hand fitting by someone who knows their stuff. Now you may spin the big wheel of fortune and be able to mount another cylinder and it may run, if you do, then you just beat all the odds.
But there are so many variables involved with the ratchet cuts, pawl / hand match up and the cylinder locking lug functions that minimizes your chances of a "drop in" success.
A visit to a qualified gunsmith with parts in hand would be my vote.