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The Powerpoint load was factory and the Nosler bullet was handloaded. Neither would have been good enough for 300 yd. prairie dog shooting but they were fine for bigger game. The Winchester load did 1" to 1 1/2". The Nosler stayed closer to an even inch in the AR, and I pretty much limited shots to about 150 yds. or less. Both bullets performed well, mostly penetrating fully at those distances. It was apparent that both expanded well. All in all, I was well satisfied with both bullets.
I doubt I'd ever use a .22 centerfire for game, but an excellent bullet advertised as a game bullet that will shoot far more accurately than the mentioned Winchester Power Point and Nosler Bond is the the 65 gr. Sierra Game King. Of course, the 65 GK probably costs more than the others, but an accurate bullet is worth the cost.
I've shot groups with this bullet to 200 yards, at which distance it is as accurate as the 69 Sierra Match King target bullet.