Started w/ a 17L, then a 21, then a 22. All very excellent pistols. Ergonomics? Never had a pistol that was ideal/perfect out of the box. Have always found something that could/should be made better. Love 1911's, but the arched MS housing and extended GS and modifying the trigger guard/grip area, sights, ejection port, throating are all areas that occasionally require attention. My little brother asked help getting a good pistol that he and his wife could use. I got him a G-19. They are not gun people. They have been very pleased with the Glock. I looked at a G-43 on Saturday. Thinking. Sincerely. bruce.