Expensive gun. Expensive ammo, Ridiculously loud. Hard kicking. A bitch to clean the muzzle break. Pretty impractical for any real use other than Big Game hunting. Heavy. If you like all those things - then get it.
IMO you could buy a few, more practical S&W's for the same money that would be a lot more pleasant to shoot, use much cheaper and readily available ammo, won't deafen you, won't beat you up and are much more fun.
I know two friends with a .500 Magnum and they rarely have shot it after the first few outings. Your money = your choice.