Miracle Man
US Veteran
The only "conditions" are proper shot placement! A poor shot with a .223 or a .30-06 is a poor shot and the animal will run. 90% of the shooters that I see at the range getting ready for deer season can't hit a "bull in the butt with a bass fiddle"! Sight alignment and trigger control will do the job, no matter the caliber.
I absolutely agree shot placement is the number 1 factor! However, "conditions" can and will contribute to a greater chance of loss of the animal with a 55 grain bullet that runs out of killing power very quickly. From the average, not very experienced, hunter.
Me, you and many others or here understand the limitations of such a small bullet, many others do not.
They'll take shots at way to far a distance. They try and shoot in high wind conditions that a 22 caliber bullet just won't cut it in. They'll try and shoot at a quartering away angle and if bone gets involved the 223 bullet blows up on the hip and doesn't produce a killing shot. One could go on.
But I'd way rather take my chances with a much heavier bullet out of a bigger gun to "help" ensure I don't wound an animal and doom it to a slow, painful death.