The skhort answer is no. The reason is that out of a revolver using rifle powder will result is really excessive muzzle flash, muzzle blast, and B/C gap flash with increased gas cutting. I love H110 for 357 Magnum rifle loads but avoid it for handgun loads because it's just too slow for a 4 or 6 inch revolver, using something even slower just isn't a good idea.
If you need pistol powder I can tell you that it can be found. However, you will have to accept that today pistol powders cost more than they did 5 years ago, so plan on spending as much as 30 dollars per pound. Then start attending every single gun show in your area. Because I've found they have been one of the most consistent sources of powder. Also, if you are within about 400 miles of Ashland/Shelby, Ohio plan on making a long drive to Fin Feather, & Fur in Ashland and the Sportsmans Den In Shelby. Because they have been another bright spot for finding powder.