I don't have any firm statistics, but in the not too recent Texas past, there were probably more homicides by .22 LR than any other caliber.
This honor probably went to 9mm at some point in the 90's, and possibly the .38 special before that, but the lowly regarded .22 has caused the demise of more than one hombre. The head shots, say the medical examiners, are the deadly ones usually, if the bullet can enter the cranium, it doesn't have much mass but has usually still a ton of velocity. Hence it tends to bouce around and around the cranium without exiting, causing extensive damage, instead of making a larger hole as a larger bullet would but with a clean entry and exit.
I would suspect many of the .22 pistols and revolvers involved in these olden days .22 homicides were of the cheap variety, and not the type of revolvers or autos any here would want to own.
That bit of obscure Texas history being said, I enjoy my 317 snubbie. The SA is great and the DA is a bit stout but it is what it is, and that's a lightweight plinking gun. I enjoy it and would buy it again if I had a do over.