Get your wife a 32-20 revolver,,then you can get a companion 32-20 Winchester rifle or carbine... Mod 73, 92, 53, etc. or maybe a Marlin in that caliber
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With all that said,,it's hard to beat a K frame S&W adj site 38special revolver in 4" bbl for an all around useful woods packin' gun. Lots of used ones available at decent prices. An M&P isn't a bad choice either if you pick your loads carefully to print to point of aim.
Reloadings a snap w/38Special,,, cases, bullets & data are all over the place. Easy to make up loads ranging from powder-puff to +P.
A 38S&W is a very decent round when handloaded. Everyone seems to want to make it comparable to a 38Special, so why not just use a 38Special.
I have a 38S&W in a Terrier and I wouldn't sell it. Great little revolver and fun to shoot but for something to spend time and effort trying to snag some game with, I'd carry something different.
I do load for it occasionally and use standard 38Spec dia cast bullets and get accuracy that is what I'd expect from the gun. Normal dia for the cartridge is .360 I believe.
Other than the Victory model, you're really rather limited in 38S&W choices, but there are some out there for sure.
Anything in '38 Colt New Police' is the same caliber from the other guys.