Bullseye Loads
I shoot bullseye with revolvers all the time. I normally shoot a Model 625-6 and the gun is superbly accurate. For the 50-yard line I shoot 4.2 Bullseye and a 185 Lead SWC. 5.0 of Win 231 is also a good load, as is 4.1 of Clays.
For the 25-yard line you can cut it WAY back. Use 3.5 of Bullseye and the 185 Lead SWC or 4.0 of Win 231.
Some guns have bad cylinders, especially the old Model 25s. I have found the H&G 78 bullet shoots great in these guns. I also have a 625-2 with oversize cylinders and the HG78 on top of 4.0 Bullseye shoots into the 10-ring at 50 yards.
I can give you the name and phone number/email of a commercial source of the HG78's. They weigh 212 grains.
I have another wonderful bullet I shoot bullseye with! It is a 185 grain FULL WADCUTTER a local fellow designed and casts for us. It cuts the biggest holes you've ever seen. So big, in fact, the holes are bigger than the plastic overlays! Shoot this on top of 4.0 of Win 231 and it shoots cloverleafs at 25 yards!
BTW, the more rounds I put through my 625 the easier it is to clean and the better it shoots! I have about 50,000 rounds through my 625-6 and it shoots better now than 5 years ago and almost no leading at all any more!