Well, let me summarize the gist of the article: 3 types of loads: 14,000psi, 20,000psi and 32,000psi.
The lowest loads are for those old single actions that were made at the turn of the century. Not black powder but not strong metallurgy either.
The next set of loads are for the Smith double action revolvers and those in that category. These are the 20,000psi loads.
Then the ones that are Thompson Center/Ruger, single and double action, and he also shoots some of these, a limited diet, in the Smith as well. I own a M25 -7. It has never seen these types of loads and probably never will. Two reasons: #1; I like my gun and wouldn't want to shoot it loose. #2: The sights. The front one is already too short for heavy bullets. If I jack up the 45-270SAA, 285gr as I cast them, to the full extent that they will take, I would have to aim 12" low @ 50 yards! Seriously! I already worked on the rear sight blade so I could get lower groups. I don't want to do that again. Now, I shoot a home cast H&G #502, Elmer's design for the 45AR, that throws a really nice 240gr LSWC, loaded with 9.0gr of Unique. Throws them at around 1000fps from the 5" tube. Wonderful and authoritative. Smacks the snot out of bowling pins, even at 50 yards!
I will post another load that I use but I want to put this up as a disclaimer: This is not for your Smith and Wesson 45 Colt revolver, um, period. I shoot this in a the aforementioned Ruger 45 caliber convertible. It has a 5 1/2" barrel. 25.0gr of H110 under that 280gr LSWC. It delivers right at 1400fps from that 5 1/2" tube. Now that is a real 45 Colt, brothers and sisters!
John Linebaugh, the famous gun smith, carries a Smith and Wesson revolver in 45 Colt. He says that they will handle the 32,000psi loads. I am going to take his word for it!
His article is online and it has his loads right in it. Take it for what it is worth and read his disclaimers. Just a suggestion though, you (and me too) aren't as smart as John, don't go beyond what he has put out. Just a suggestion. You do as you want. (Directed at whoever reads this and no one in particular)