Titegroup generally works well with lead bullets, but there are exceptions to everything. Before you give up on it, decrease your powder charge, then increase it and shoot some magazine-full groups from a solid benchrest at twenty-five yards, checking both accuracy and possible leading after each group.
If these bullets worked before and don't work now, they may be undersized. If you have a micrometer (a caliper won't work), check to make sure they measure .452". I doubt hardness between the good batch and bad batch varied enough to matter, but decreasing and increasing your charge until leading stops will help you eliminate this variable.
I think I may have tried this bullet years ago, but don't recall for sure. Good luck in your endeavor-