My experience with 45 ACP's out of revolvers is very positive. I have 3 I shoot. A 625-8 that is a 4" with custom rnd to sq wood grips. It is the model that was the basis for the "JM", but isn't a JM. I bought it new and had S&W do the "master revolver package" on it, and it is one of my all around favorites. I also have 2 25-2's. One I shoot, and one that is pristine, and is currently for sale. They are the gun that really carried the whole moon clip tradition into the modern age, and they still are, in my view-there's just something about them. Then, I have a 25-5 8 3/8's barrel that I sent off (for a long time) and had quite a bit of work done on, including having the cylinder machined so that it would shoot 45AP's a well as 45Colts. This is not a pinned barrel m-25-5, and has .451 cylinder throats, as opposed to earlier guns with over sized throats. It took some work to get the right bullet loaded for it, but it is incredibly accurate, an has practically no recoil. It's like the 45 ACP was intended for revolvers!