If it's a home based business (and an 01FFL IS a business, not a hobby), it must comply with all Local Zoning Laws, Codes and Ordinances.
Signage, Fire, Insurance, Handicap Access, Firearm and Powder storage, security, parking, lighting and on and on.
Some areas are easier to deal with than others by far. Check first if they even allow a home based Fireearms related biz in your zipcode/area/residence if that is what you have in mind.
If you can't meet that simple bar,,you won't be issued the FFL.
It's a Business,,so you will be paying taxes on whatever profit you make, filing the proper Tax forms, etc.
After that it's making sure everything is run as the ATF Book says.
Short cutting the rules will make your business life a short one.
ATF compliance checks are a
sure thing and not always announced before hand.
The 'Business Hours' you must list on the application and renewal are the 'walk-in' hours that the ATF can visit you to check your biz records.
It has nothing to do with the public and doing business with them.
I had ATF checks that were done by them calling first and setting up the time & day. But also blind visits where they just showed up as well.
The checks usually lasted a full business day /plus a couple more hrs.
A few two days.,,and that was just for me as a single prop with a gunsmithing/engraving biz plus buy/sell usually around 40guns per 3yr lic period.
50yrs in it. Out of it now for the last 3 or 4 yrs.
Right now it's the State and local laws that have made it more difficult at least here (NYS) but the Fed regulations are more confusing every yr as well.
You must stay on top of all the laws and changes. Record keeping must be top knotch.
'No excuses excepted' is the general rule from the Gov't.
That's the reason many FFL's opt to the CYA side of anything even remotely seen as unclear in the regs.