I"ve used the auto disks for decades on my original turret press and then the Loadmaster, and find them to be just fine with the ball powders I prefer. (They also work well with Trail Boss, which is like big, thin washers in shape, but it's a fill-up-the-case powder so it needs large cavities, and the powder fills those pretty consistently.) I have several of the adjustable charge bars, and they too have worked fine for me as long as I'm not trying to throw too small a charge - I forget where the lower limit is, but I think even Lee recommends use only above a certain volume.
I find the disk design to be a super reliable and repeatable system, subject to the limitations of its fixed steps. For most of my handgun loads, though, I have found that one of the holes will give a consistent charge that's about right for what I need, and I haven't been bothered by the fact that I can't throw a charge that's 0.3g more or less. On those infrequent occasions when I was loading near-max loads, I used a bench mounted (Redding) measure that I could dial up to just where I wanted it. But for the bulk stuff I loaded most, the disks were fine.
I am now loading a lot of 32 revolver rounds, including 32 H&R and 327 Federal Magnum. These don't need very large charges for most loads, and the spread between minimum and maximum charge can be pretty small. So I've made my own "adjustable" disks by drilling and tapping a hole into each one of the measuring holes on a disk, and turning in a set screw that I can drive into and out of the cavity to tune it for a precise charge of a particular powder. (I have bought a LOT of disk measures over the years, and so have a spare set of disks I can modify just for this purpose.)
I work up a particular load using the bench mounted measure, making 10-20 rounds at a each of several charge levels, which I then chronograph and shoot for accuracy. When I find one I like, and want to load in quantity, I'll figure out which disk will throw just above the charge I want, and turn the set screw in or out to get the precise charge. The 0.53 disk, for example, throws 3.4g of Red Dot after I've adjusted the screw to slightly reduce its normal volume.