First off, I really like my new 22c. Doesn't come close to my Browning Buck Mark, but I didn't expect it to. Bought it as an addition to my growing M&P family and as a range/plinker.
As with most 22 pistols, and with the above posts for comparison; it'll depend on what the individual gun/pistol likes, as to what it will shoot well/reliably. So far, the only 2 brands of ammo my 22c will shoot without issue is American Eagle (AE22) and Federal (510). I've tried at least 6 different loads in my 22c and the results are a little frustrating (to me), when I see others who have better luck with some of the same ammo I have issues with.

Again, this is a range/plinker pistol for fun at the range, I WOULD NOT recommend a 22 rimfire for self defense, but that's just me. I have far more issues with 22 ammo than I do the 22c, surprisingly, the better/more "premium" stuff that cost more $$$.
I'm not going to give up on the 22c, I don't have near enough rounds down range through this little pistol! And at some point, I will no doubt add a FS 22 to the collection. And some folks have really good luck with the FS and some folks don't-again, I feel it's the individual pistol and quality of 22 ammo that dictates the results. Buy one and enjoy it for what it is.