My Grand father was in 497th BOMB GROUP B-29s under Gen Curtis LeMay on Saipan. He said that the big raids on major cities would have 100 B-29s.
They would routinely lose 10% of aircraft or 100-110 men per day.
100 aircraft is not a big raid . There were some missions where the U.S. and British put up 1000 aircraft . That's hard to imagine .