I have done that........If you already have the scope and the barrel has the picatinny mount, go ahead and give it a try.
Probably will not like it.
I tried it and did not notice any increase in accuracy when benched and 4 power is too powerful to hold either one handed or two handed. Your fighting the scope trying to get a image to appear as you are holding it on target.
For what it is worth, I am a expert level bullseye shooter and regularly check accuracy of my teammates handguns off a bench to verify it is the shooter and not the equipment. I also have a model 41 barrel with a old Bushnell 1.6 power scope that can be kicked up to 2.6 with a lens that screws on the front. 1.6 power is doable but I do not like it. 2.6 is impossible.
I have a ultra dot red dot on my Ruger 44 magnum revolver and routinely hit milk jugs at 50 yards, about half the time at 100 yards with the revolver. Took a 2.5 power scope off of it and my accuracy improved along with my enjoyment.
Like I said, if you already have the scope go for it but I would not invest any money in it with my experience.
Regards,
Crankster