I’ve conceal carried for 36 years, and carried a 1911 for much of that time.
I normally carry IWB, but it’s worth noting the only times I have ever had a safety come off during the day is when I was carrying a 1911 with an ambidextrous safety.
It’s clearly important for a lefty, and some of the go fast tacti-cool set will dream up a scenario to justify having one on a right hander’s p 1911. But the fact is for concealed carry, as well as any situation where you may be down on the ground rolling around, that ambidextrous safety is far more likely to get inadvertently moved to the “fire” position of you are a right handed shooter.
That said, the dozen or so times it has happened, it’s been noticed when removing the handgun for the night and I normally do that by unclipping the holster, so the trigger remains covered.
The couple times where I removed the gun from the holster, good trigger discipline and keeping the trigger finger indexed on the frame prevented any potential negligent discharge.
The same is true in pocket carry. You have to be 100% consistent in drawing it from the holster and indexing your finger on the frame until the gun is pointing safely down range.
Doing that under extreme stress requires it be well practiced - with perfect practice - to the point that is an unconscious muscle
memory act to keep your finger *off* the trigger.
