I have found in 38 special that .2 grain can make a big difference in accuracy with some powders. What I typically do is build 15 rounds of each .2 grain increment of powder weight starting with the minimum load working up to max. Then off to the range to shoot from a rest. Usually I'll find the most accurate charge weight at around the 60-75% area of charge weight range for that load. Be aware that your grip, even from a rest can have a big factor on how the rounds group. Be consistent with your grip going so far as to take the gun out of your hand and re-establish your grip between each round. I recently worked up a load for 38 spcl 148 grn plated double ended wad cutters with W231 powder. Started at 2.4 grains and worked up to 3.6 in .2 grn increments. I found a good group at 2.8 grns, but an even tighter group at 3.4 grns, so that is what I'll be using for that 4" Ruger Blackhawk. Every gun is different, and the beauty of this hobby is that you can experiment and find what works best in your gun, usually exceeding the performance of factory ammo.