Unfortunately, no, the Single-six is considerably smaller than the Vaquero, which is the same frame size as the Blackhawk.
Even the New Vaquero will still fit the same size holster as the old one, but is still vastly larger than the Single-six.
Do you want a leather or a nylon holster?
There aren't as many choices for the Single-six as there are for the Vaquero/Blackhawk, but there are a good many from various manufactures such as Old El Paso, Galco, Hunter, Mitch Rosen, and many others.