I agree with all the votes for the 27, but, you could pack a whole lot of extra power, and therefore uses in the same size package, with a 29/629 with 3"-4" barrel. But then again I sleep, eat, and drink N-Frame 44's.
I bought a 27-2 6" nickel a few months ago. I brought it home & stuck it in the safe. After reading this thread, I got it out & examined it. It really is the top of the line for S&W ,...top of the line for any revolver.... IMO.