I have both 22-250 and a couple 223.
TC contender in 223. Good little gun, vertical stringing is possible as it heats up.
Remington 700 VL (Varmint Laminated Bull Barrel) Great 22-250. Sits in the safe a lot, its almost too nice to bring out. I have shot offhand rifle matches with this one for the last few years. Its a great shooter.
Savage model 25 Lightweight Varminter. 8.5 lbs with thumbhole stock before I put the scope on it. 223, not 5.56.
The Savage is a great gun. The bolt works with one finger, no problems with the gun. Trigger is an accutrigger. I adjusted it all the way down as soon as I bought the gun. Its at 32 oz with no gunsmithing. Far better than the Remington.
I bought the 223 because ammo and component availability. Right now my reloading setup is out of use, so I am buying ammo for 1/2 the cost of 22-250.
Most of my shooting is 100 or 200 yards offhand with the occasional 300 shot. 223 is fine for all that.
I shoot an offhand rifle match every saturday morning. Both rifles do well except if I use the savage then the remington and realize how much the trigger in the remington sucks. 100 or 200 yards shooting at paper, it makes no difference how fast the bullet is going.
223 takes 21 to 26 grains powder. 22-250 takes almost 40 grains.
I am buying Hornady 55 gr FMJ or 55 gr SP 500 for $49.00. That is the same as I buy bullets for my 45 ACP.
Right now I am shooting the savage (223) once or twice a week. The remington sits in the safe.
In an earlier life, I had a Savage model 110 in 7mm mag. I shot chucks with that and hunted deer. In a few years the rifling was eroded 1/2 way up the barrel and I sold the gun. 115 gr @ 3500 makes a chuck turn to pink mist. I don't miss that gun at all. It kicked the stuffing out of me.
Savage Model 25 LVT
David