I know I just like to fondle them. Sometimes I get mad at one or two and sell them. I sure wish I could turn a profit, but in reality I'm real lucky to break even. And I've lost some money on one or two...or more.
But we need to keep the terminology straight. To the best of my limited knowledge, all S&Ws go through an inspection step where every other cylinder is loaded and fired. It might be called "proof of function". And over the years I've owned and looked at a bunch of guns. Its not at all uncommon to discover the factory didn't bother to clean the gun after firing. If you want an unfired gun, don't buy a S&W. Or a Swiss SIG. There is no magic to "unfired". Just accept the concept that every single gun you buy or handle has been fired.
If you have a new gun that you want to shoot, just for the stupid pleasure of saying dumb things like you've shot all your guns, its OK. If you've got some sense (a stretch), look carefully at the cylinder. You'll probably discover which cylinders were used. So just reload those 3 and have at it.

Then if you've got good hands and skills, you can clean the gun really well and then it'll look as if you haven't shot it at all, and it skipped the QC step at the factory.
But then you could shoot a gun a few times and then clean it really well. To the uninitiated, it would appear unfired. And some common sense. Don't holster the gun, ever. Not even a single time. And don't eject the fired rounds. Bring along your old cleaning kit. No, not the sealed on in the box. Bring another, used on. Just the jag and individually punch out the fired cases. When you exercise the ejector rod, you scratch it each time. Over a couple of shooting sessions, you wear it enough that any old fool can see the usage.
But there is also the idea that you, the shooter, want the gun to look well used. Maybe you just like the idea of doing senseless damage. If you've paid the price for the gun, go ahead and make it a gun of less value. I don't care because mine mostly remain pristine. And every gun you mess up makes mine worth more.

So the most sensible thing to do is shoot the guns you normally shoot. And not shoot the best examples if you have any sense at all (I know, sense is a rare commodity.)
And the comment about how many guns you have is well placed. The only K22 I shoot these days is K155. Its a good gun, or maybe a really good gun, but it was well fired when I got it. I clean it after every session, but its the only K22 from a selection I will fire. We could go on to discuss 357s, or even 44s. Same deal. Pick one and shoot it. In the past I've bought other used guns and fired them a bit, just because that's why I bought the gun. But those weren't new guns but once. And when they came to me, they needed shootin'.
So do as you please. If you're stupid, you make my guns worth more and yours less valuable. I don't mind, but if you see me smiling, its not because I think you're smart.